Paridhi (Pari) Latawa
Bacterial Antiviral Defense Systems
2024–2025
Electrical Engineering and Computer Science
- Biology
Regina A. Barzilay
Feng Zhang
In response to viral infection, bacteria have antiviral phage defense systems that facilitate the bacterial response to phage attack. Various phage defense systems have been previously identified, but the behavior and functionality are not fully characterized. This research focuses on exploring phage defense systems such as the Class 2 UG Reverse Transcriptase (RT) defense system through computational and wet-lab analysis. By further understanding the mechanism of RT systems, we can engineer them to produce desired proteins or express activities of interest or express activities of interest.
The SuperUROP experience will be an engaging opportunity to explore computer science and biology through hands-on, cutting-edge, collaborative research. Through this experience, I hope to integrate my knowledge in AI/ML and biology together in a research setting with real-world applications while gaining mentorship and guidance through SuperUROP!