Paridhi (Pari)  Latawa

Paridhi (Pari) Latawa

Research Title

Bacterial Antiviral Defense Systems

Cohort

2024–2025

Department

Electrical Engineering and Computer Science

Research Areas
  • Biology
Supervisors

Regina A. Barzilay

Feng Zhang

Abstract

In response to viral infection, bacteria have antiviral phage defense systems that facilitate the bacterial response to phage attack. Various phage defense systems have been previously identified, but the behavior and functionality are not fully characterized. This research focuses on exploring phage defense systems such as the Class 2 UG Reverse Transcriptase (RT) defense system through computational and wet-lab analysis. By further understanding the mechanism of RT systems, we can engineer them to produce desired proteins or express activities of interest or express activities of interest.

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The SuperUROP experience will be an engaging opportunity to explore computer science and biology through hands-on, cutting-edge, collaborative research. Through this experience, I hope to integrate my knowledge in AI/ML and biology together in a research setting with real-world applications while gaining mentorship and guidance through SuperUROP!

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