Kristin Sheridan

Kristin  Sheridan
MIT SoE | Quest Undergraduate Research and Innovation Scholar
Advisor: Mark Bathe
Department: Biological Engineering/UBIOME
Areas of Research: Biological Engineering
Years: 2018-2019
Research Project Title:

DNA-Based Fuzzy Addressing for Memory Storage

abstract:The small size and slow degradation rate of DNA give it the potential to act as a long-term storage material for large databases. However, searching such databases for files with specific properties poses a challenge because unique addresses contain limited information about the file and make it difficult to find all files with a given property without individually sequencing every strand. We are working on developing an addressing system in which short DNA tags provide information about a file that makes it searchable by a complementary DNA probe. The limited specificity of DNA binding allows for the development of a “fuzzy” addressing system in which a search for a specific property will find most files with the property exactly matching the search term and some files with similar properties.

“I am excited to participate in SuperUROP to learn skills in research planning and execution. I hope that I can apply the lab skills I have learned in previous research experiences to a project that I am able to help design. The project I am working on is also more computational than research I have done in the past, so I am excited to work on my abilities in that area.”