Karen  Jiang

Karen Jiang

Research Title

Gas-Based Sensors for Gastrointestinal Diseases and the Environment

Cohort

2025–2026

Department

Mechanical Engineering

Research Areas
  • Mechanical Engineering
Supervisor

Traverso, Giovanni

Abstract

Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) affect a large portion of the population but remain difficult to diagnose due to overlapping symptoms and the lack of reliable biomarkers. Gaseous species such as hydrogen sulfide have been implicated in gut physiology and may serve as direct indicators of inflammation, motivating the development of a device that connects to an endoscope to sample intestinal gases during endoscopy and colonoscopy procedures. Similarly, methane emissions from ruminant animals represent a critical challenge in climate change mitigation, as livestock are among the largest contributors to global greenhouse gas emissions. Monitoring the effects of feed modulation on enteric methane production requires scalable, real-time tracking. To address this, an orally deliverable device is being developed to remain in the rumen and continuously monitor methane levels. Building on these parallel efforts, this work will involve clinical data collection with the devices, mechanical refinement of the designs, and electrical development and characterization of gas sensors.

Quote

I am participating in SuperUROP to gain hands-on experience in developing medical and environmental technologies that address real-world challenges. This offers the opportunity to work directly on device design, sensor development, and in vivo studies, connecting engineering principles with clinical applications. Through these projects, I hope to deepen my technical skills while contributing to impactful solutions for human health and sustainability.

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