Jonathan  Chien

Jonathan Chien

Scholar Title

MIT EECS - Draper Laboratory Undergraduate Research and Innovation Scholar

Research Title

Engineering and Characterization of a Synthetic Genetic Parts Library

Cohort

2012–2013

Supervisor

Timothy K. Lu

Abstract

Synthetic biology aims to combine electrical engineering design principles with living organisms. Recently, many electronic parts such as digital logic gates, band-pass filters, and pulse generators have been implemented in cells through synthetic genetic circuits. However, one of the current limitations is the lack of availability of a variety of reliable, modular, and well-characterized parts. My project aims to construct, characterize, and optimize a library of genetic circuit components. Once the library is established, the next goal is to use the parts in a computational model or a complex genetic circuit that introduces novel functions into eukaryotic cells.

Quote

I have interned at Alexion Pharmaceuticals investigating the role of mass transfer in different scales of bioreactors. I was a member of the 2011 MIT iGEM team and worked on building cells that could self-construct into tissues. Im interested in the use of technology to improve the quality of life for impoverished communities around the world.

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