MIT EECS - Texas Instruments Undergraduate Research and Innovation Scholar
Noninvasive estimation of intracranial pressure: algorithms, instrumentation, and clinical validation
George C. Verghese
To measure intracranial pressure (ICP), neurosurgeons drill a hole into the skull to advance a catheter or sensor. Given the risk of infection, this procedure is reserved for cases of extreme head trauma, limiting the use of ICP in directing therapies to treat strokes, hydrocephalus, and other similar conditions. To address this problem, we are developing a noninvasive ICP monitoring system using commercially available hardware. We will improve our existing model-based algorithm for ICP estimation by validating it against data from the Beth Israel Deaconess Medical Center, as well as automating it for our real-time system.
I have worked with Prof. Fatih Yanik and Cody Gilleland to develop a high-throughput C. elegans injection system; and in the Operations Planning Software Lab at the Jet Propulsion Laboratory developing a cloud-based, augmented-reality platform to facilitate engineering design collaboration. In our ICP project, we are using data from Addenbrookes Hospital in Cambridge University to test our algorithm.